Recent research in Alzheimer's disease and related dementias (AD/ADRD) has shown promising results, with several drugs demonstrating potential in clinical trials. Conducting multicenter clinical trials for AD/ADRD is a complex process that requires the collection and management of vast amounts of data from multiple sources. To ensure the success of these trials, ATRI's Informatics Section, led by Gustavo Jimenez-Maggiora, has developed the ATRI electronic data capture system (ATRI EDC).
The ATRI EDC system uses agile, cloud-native software development methods to ensure that it can adapt to rapidly evolving research designs and technologies. The system is customizable to meet the specific needs of individual studies and supports a high degree of study-specific configurations. It also encourages collaboration among researchers and promotes the principles of open science.
To date, the ATRI EDC system has been used in 10 clinical studies involving over 4,500 participants, demonstrating its effectiveness in managing data in multicenter clinical trials for AD/ADRD. With continued development and community-building efforts, the system has the potential to improve the overall effectiveness of clinical studies for AD/ADRD and other conditions.
